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Prevalence of mitochondrial DNA disease in adults

Some travelers bring a separate food cooler that they refresh with store-bought ice, and nestle their medication cooler inside it for double insulation

Prescription and administration: Once B12 deficiency is confirmed, GPs prescribe hydroxocobalamin injections according to standardised protocols: Standard loading regimen: 1mg intramuscularly three times weekly for two weeks Neurological involvement: 1mg intramuscularly on alternate days until no further improvement Maintenance therapy: 1mg every three months for life in pernicious anaemia or malabsorption conditions (or every two months if there was neurological involvement) Injections are typically administered by practice nurses at GP surgeries

Nonetheless, only about 0.5% of teens with obesity received any such medication in 2023

Proceedings of the National Academy of Sciences of the United States of America, 108(37), 1503715042