Rat Caspase-2, CASP2 ELISA Kit, 96T Endonucleases & Exonucleases and deficiency of this protein

and deficiency of this protein has been associated with liver disease

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leading to the recruitment of TIR-containing downstream adapter MYD88 through homotypic interaction

enhances recruitment of TAF4 to CREB1

Gene Ontology (GO) annotations related to this gene include calmodulin binding and Ras GTPase binding

Rat Caspase-2, CASP2 ELISA Kit, 96T Endonucleases & Exonucleases and deficiency of this proteinInvolved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival (By similarity). Associates with PIDD1 and CRADD to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis in response to genotoxic stress (By similarity).