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RUNX1 Monoclonal Antibody, 50ul[BT-MCA1115] Custom DNA Oligos This protein is present in

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RUNX1 Monoclonal Antibody, 50ul[BT-MCA1115] Custom DNA Oligos This protein is present inCore binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have

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Description

This protein is present in all hematopoietic lineages

The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1 and P2 dimers

An important paralog of this gene is HMP19

This protein can be phosphorylated by tyrosine kinases

Pro-apoptotic WT1 regulator is specifically upregulated during apoptosis of prostate cells

RUNX1 Monoclonal Antibody, 50ul[BT-MCA1115] Custom DNA Oligos This protein is present inCore binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have

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