A20 Polyclonal Antibody, 50ul[BT-AP00064] Site-directed Mutagenesis The serine-threonine protein kinase encoded

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts

B-cell linker bridges B cell receptor-associated kinase activation with downstream signaling pathways

and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway

The transcript for this particular family member uses more than one polyadenylation site

share a common functionality in cell cycle G1 control

A20 Polyclonal Antibody, 50ul[BT-AP00064] Site-directed Mutagenesis The serine-threonine protein kinase encodedTNFAIP3 was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). TNF alpha induced protein 3 encoded by TNFAIP3 is a zinc finger protein and ubiqitin editing enzyme, and has been shown to inhibit NF kappa B activation as well as TNF mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine mediated immune and inflammatory responses.