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MerTK Polyclonal Antibody, 20ul Antibody Development The FGR proto-oncogene

SKU: 49883996972

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MerTK Polyclonal Antibody, 20ul Antibody Development The FGR proto-oncogeneMERTK is a member of the MER AXL TYRO3 receptor kinase family and encodes a transmembrane protein, tyrosine protein kinase mer, with two fibronectin type III domains, two Ig like C2 type (immunoglobulin like) domains, and one tyrosine kinase domain. Mutations in MERTK have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

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Description

The FGR proto-oncogene

The activity of the protein is negatively regulated by its SH3 domain

TRAK2 (Trafficking Protein

user-friendly design

Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections

MerTK Polyclonal Antibody, 20ul Antibody Development The FGR proto-oncogeneMERTK is a member of the MER AXL TYRO3 receptor kinase family and encodes a transmembrane protein, tyrosine protein kinase mer, with two fibronectin type III domains, two Ig like C2 type (immunoglobulin like) domains, and one tyrosine kinase domain. Mutations in MERTK have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

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