RBQ-3 Polyclonal Antibody, 100ul Cell Screening and Imaging This complex (anaphase promoting complex

This complex (anaphase promoting complex subunit 1) is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation

This kinase is activated by mitogenic and environmental stress

The protein encoded by this gene is closely related to STAM| an adaptor protein involved in the downstream signaling of cytokine receptors| both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM)

This gene has multiple pseudogenes and is a member of the phosphatidylinositol glycan anchor biosynthesis gene family

Acts by interacting with the second WW domain of ITCH

RBQ-3 Polyclonal Antibody, 100ul Cell Screening and Imaging This complex (anaphase promoting complexRBBP5 (RB binding protein 5, histone lysine methyltransferase complex subunit) encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A binding pocket B. Three alternatively spliced transcript variants