Porcine Signal Transducer and Activator of Transcription 1, STAT1 ELISA Kit, 96T Culture Tubes It functions as a DNA-binding
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Porcine Signal Transducer and Activator of Transcription 1, STAT1 ELISA Kit, 96T Culture Tubes It functions as a DNA-bindingSignal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG SCF and other cytokines and other growth factors. Following type I IFN (IFN alpha and IFN beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G IRF 9 to form
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