MDM2(Phospho Ser166) Polyclonal Antibody, 20ul Metabolic enzymes Isoform 1 is involved in

Isoform 1 is involved in UBTF-activated transcription

This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release

This protein has been shown to be up-regulated in tumors| especially in breast tumors| and thus it is associated with tumor invasiveness

also designated Ubiquitin D or Diubiquitin

is located on chromosome 6

MDM2(Phospho Ser166) Polyclonal Antibody, 20ul Metabolic enzymes Isoform 1 is involved inThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript