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CD13 Polyclonal Antibody, 50ul[BT-AP01347] Custom DNA Oligos Down-regulated in melanoma tissue

SKU: 50103701496

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SEK162.00 SEK188.00

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CD13 Polyclonal Antibody, 50ul[BT-AP01347] Custom DNA Oligos Down-regulated in melanoma tissueAminopeptidase N is located in the small intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus

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Description

Down-regulated in melanoma tissue

Mutations in dysferlin| a protein associated with the plasma membrane| can cause muscle weakness that affects both proximal and distal muscles

These variants encode at least five different isoforms

CANX encodes a member of the calnexin family of molecular chaperones

This protein is thus a potential drug target for the treatment of muscle atrophy

CD13 Polyclonal Antibody, 50ul[BT-AP01347] Custom DNA Oligos Down-regulated in melanoma tissueAminopeptidase N is located in the small intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus

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