HNF6 Polyclonal Antibody, 100ul Culture Plate Inserts The C region genes are

The C region genes are clustered downstream of the V region genes within the heavy chain locus on chromosome 14

This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress

Two transcript variants encoding the same protein but differing in the 5' UTR

Mutations in this gene are associated with ataxia telangiectasia| an autosomal recessive disorder

They also have different biochemical properties and developmental profiles

HNF6 Polyclonal Antibody, 100ul Culture Plate Inserts The C region genes areThis gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver expressed genes, and antagonizes glucocorticoid stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple