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RUNX3 Polyclonal Antibody, 100ul[BT-AP08063] DNA Fragments Expression of this protein also

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RUNX3 Polyclonal Antibody, 100ul[BT-AP08063] DNA Fragments Expression of this protein alsoRUNX3 encodes a member of the runt domain containing family of transcription factors. A heterodimer of this Runt related transcription factor 3 and a beta subunit forms a complex that binds to the core DNA sequence 5' PYGPYGGT 3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or

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Description

Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis

Mutations in TMPRSS15 cause enterokinase deficiency

The protein encoded by this gene is a DNA binding and apoptosis-inducing protein and is localized in the nucleus

or it can remain intracellular

It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses

RUNX3 Polyclonal Antibody, 100ul[BT-AP08063] DNA Fragments Expression of this protein alsoRUNX3 encodes a member of the runt domain containing family of transcription factors. A heterodimer of this Runt related transcription factor 3 and a beta subunit forms a complex that binds to the core DNA sequence 5' PYGPYGGT 3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or

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