KLHL3 Polyclonal Antibody, 100ul Cell Transfection In mammalian cells

In mammalian cells

These desmosomal family members

and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions

The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases

including influenza A virus

KLHL3 Polyclonal Antibody, 100ul Cell Transfection In mammalian cellsKLHL3 is ubiquitously expressed and encodes kelch like family member 3 which has an N terminal BTB domain followed by a BACK domain and six kelch like repeats in the C terminus. These kelch like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare