Dab1(Phospho-Tyr220) Rabbit Polyclonal Antibody, 20ul Cell fragmentation and collection ROBO proteins are a subfamily

ROBO proteins are a subfamily of the immunoglobulin transmembrane receptor superfamily

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This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation

Studies of a similar gene in zebrafish suggest that it is important for axon pathfinding in the developing nervous system

The protein consists of a tetramer of identical subunits

Dab1(Phospho-Tyr220) Rabbit Polyclonal Antibody, 20ul Cell fragmentation and collection ROBO proteins are a subfamilyThe laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice the disabled 1 gene plays a central role in brain development directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled 1 and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to