TRPC3 Polyclonal Antibody, 100ul Cellular Function Assays Mutations in this gene have

Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome

Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation

and cell motility

IQCB1 encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein

Pseudogenes associated with PDLIM1 are located on chromosomes 3

TRPC3 Polyclonal Antibody, 100ul Cellular Function Assays Mutations in this gene haveShort transient receptor potential channel 3 encoded by TRPC3 is a membrane protein that can form a non selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene.