CLD22 Polyclonal Antibody, 20ul Protein Post-translational Modification It is an autocrine growth

It is an autocrine growth factor as well as a mitogen for astrocytes

The BIR domain is essential for inhibitory activity and interacts with caspases

The protein is thought to play a role in the process of inflammation and tissue remodeling

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It is expressed in the dorsal telencephalon during development in a low rostral-lateral to high caudal-medial gradient and is proposed to pattern the neocortex into defined functional areas

CLD22 Polyclonal Antibody, 20ul Protein Post-translational Modification It is an autocrine growthThis gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and overlaps the 3' UTR of the WWC2