p57 Polyclonal Antibody, 100ul[BT-AP06843] Mechanical Pipette This gene is a member

This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation

AURKB (aurora kinase B) encodes a member of the aurora kinase subfamily of serine/threonine kinases

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This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb)

Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6)

p57 Polyclonal Antibody, 100ul[BT-AP06843] Mechanical Pipette This gene is a memberCDKN1C is imprinted, with preferential expression of the maternal allele. The cyclin dependent kinase inhibitor 1C is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that CDKN1C is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been