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TH Polyclonal Antibody, 50ul[BT-AP08989] Plasma AKR1A1 encodes a member of

SKU: 51184614226

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USD162.00 USD211.00

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TH Polyclonal Antibody, 50ul[BT-AP08989] Plasma AKR1A1 encodes a member ofThe protein encoded by TH (tyrosine hydroxylase) is involved in the conversion of tyrosine to dopamine. It is the rate limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in TH have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for TH.

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Description

AKR1A1 encodes a member of the aldo/keto reductase superfamily

Ikaros/Aiolos heterodimers

which appears to have increased activity

The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes

A read-through INS-IGF2 gene exists| whose 5' region overlaps the INS gene and the 3' region overlaps this gene

TH Polyclonal Antibody, 50ul[BT-AP08989] Plasma AKR1A1 encodes a member ofThe protein encoded by TH (tyrosine hydroxylase) is involved in the conversion of tyrosine to dopamine. It is the rate limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in TH have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for TH.

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