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p53 Polyclonal Antibody, 20ul[BT-AP06833] Pathway and Network Analysis The nuclear pore complex (NPC)

SKU: 5123594227

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p53 Polyclonal Antibody, 20ul[BT-AP06833] Pathway and Network Analysis The nuclear pore complex (NPC)TP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

The nuclear pore complex (NPC) mediates bidirectional macromolecular traffic between the nucleus and cytoplasm in eukaryotic cells and is comprised of more than 100 different subunits

Sulfatases (EC 3

CD30 ligand (CD30L)/TNFSF8 is a type II membrane protein belonging to the TNF superfamily

FAT10 is inducible by interferon-g and tumor necrosis factor a (TNF)

PTCH1 (patched 1) encodes a member of the patched gene family

p53 Polyclonal Antibody, 20ul[BT-AP06833] Pathway and Network Analysis The nuclear pore complex (NPC)TP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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