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TBX15/18 Polyclonal Antibody, 50ul Protein Modification The encoded protein is important

SKU: 51423318067

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TBX15/18 Polyclonal Antibody, 50ul Protein Modification The encoded protein is importantTBX18 codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA binding T box domain and is divided into five sub families based on sequence conservation in this domain. The T box transcription factor TBX18 belongs to the vertebrate specific Tbx1 sub family. The protein acts as a transcriptional repressor by antagonizing

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Description

The encoded protein is important in the establishment of the radial glial fiber in the developing brain

An important paralog of this gene is ERAP2

The specific function of this particular member has not been determined

Proteins expressed using the baculovirus-insect expression system retain full biological functionality and can accommodate larger exogenous fragments

This protein belongs to the Pmr5-Cas1p-esterase subfamily in that it contains the catalytic triad comprised of serine| aspartate and histidine and lacks two conserved regions (glycine after strand S2 and GxND motif)

TBX15/18 Polyclonal Antibody, 50ul Protein Modification The encoded protein is importantTBX18 codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA binding T box domain and is divided into five sub families based on sequence conservation in this domain. The T box transcription factor TBX18 belongs to the vertebrate specific Tbx1 sub family. The protein acts as a transcriptional repressor by antagonizing

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