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p23(Phospho Ser113) Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing PAI-2 occurs in secreted and

SKU: 5147748133

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p23(Phospho Ser113) Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing PAI-2 occurs in secreted andThis gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes.

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Description

PAI-2 occurs in secreted and cytosolic forms through facultative polypeptide translocation

The protein thus belongs to the suppressor of cytokine signaling (SOCS) family

The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion

Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors

This gene encodes a cell-surface protein that is similar to CD99

p23(Phospho Ser113) Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing PAI-2 occurs in secreted andThis gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes.

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