ST2A1 Polyclonal Antibody, 20ul[BT-AP14509] Buffers & Solutions Alternative splicing of PIK3R1 results

Alternative splicing of PIK3R1 results in four transcript variants encoding different isoforms

Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus

Mutations in these genes have been associated with White Sponge Nevus

Cyclin F encoded by CCNF belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified

The recognition component of this pathway

ST2A1 Polyclonal Antibody, 20ul[BT-AP14509] Buffers & Solutions Alternative splicing of PIK3R1 resultsThis gene encodes a member of the sulfotransferase family. Sulfotransferases aid in the metabolism of drugs and endogenous compounds by converting these substances into more hydrophilic water soluble sulfate conjugates that can be easily excreted. This protein catalyzes the sulfation of steroids and bile acids in the liver and adrenal glands, and may have a role in the inherited adrenal androgen excess in women with polycystic ovary syndrome.