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UT2 Rabbit Polyclonal Antibody, 50ul ssDNA Synthesis GPR110 is a gene on

SKU: 51664792876

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SEK185.00 SEK206.00

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UT2 Rabbit Polyclonal Antibody, 50ul ssDNA Synthesis GPR110 is a gene onThe protein encoded by this gene belongs to the urea transporter family. In mammalian cells urea is the chief end product of nitrogen catabolism and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene.

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Description

GPR110 is a gene on chromosome 6p12

but it is expressed in hematopoietic tissues and appears to be restricted to primitive stem cells present in those tissues with functions in blood and vessel development

and is implicated in the transcriptional regulation of Hox genes and cytokines

This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases

but not glucocorticoid receptor

UT2 Rabbit Polyclonal Antibody, 50ul ssDNA Synthesis GPR110 is a gene onThe protein encoded by this gene belongs to the urea transporter family. In mammalian cells urea is the chief end product of nitrogen catabolism and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene.

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