HACE1 Polyclonal Antibody, 20ul Vector Construction PABPC4 contains 4 RNA-binding domains

PABPC4 contains 4 RNA-binding domains and proline-rich C terminus

Mutations in this gene are associated with two types of recessive osteochondrodysplasia| Dyggve-Melchior-Clausen (DMC) dysplasia and Smith-McCort (SMC) dysplasia| which involve both skeletal defects and mental retardation

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The true nature of the physiological cofactor is under debate

This gene encodes a member of the uroplakin family

HACE1 Polyclonal Antibody, 20ul Vector Construction PABPC4 contains 4 RNA-binding domainsThis gene encodes a HECT domain and ankyrin repeat containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor.