BLMH Rabbit Polyclonal Antibody, 20ul Miscellaneous Mutations in PAX8 have been

Mutations in PAX8 have been associated with thyroid dysgenesis

|enzyme regulation:Cannot be activated without removal of the activation peptide

The resulting trimer binds to DNA with high specificity and affinity

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This protein has been shown to deplete reactive oxygen species

BLMH Rabbit Polyclonal Antibody, 20ul Miscellaneous Mutations in PAX8 have beenBleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily.