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TRADD Polyclonal Antibody, 100ul Hepatocytes consisting of a homodimer of

SKU: 51865775390

4.2
SEK123.75 SEK161.75

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TRADD Polyclonal Antibody, 100ul Hepatocytes consisting of a homodimer ofTumor necrosis factor receptor type 1 associated DEATH domain protein encoded by TRADD is a death domain containing adaptor molecule that interacts with TNFRSF1A TNFR1 and mediates programmed cell death signaling and NF kappaB activation. Tumor necrosis factor receptor type 1 associated DEATH domain protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor of apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated

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Description

consisting of a homodimer of accessory subunits plus a catalytic subunit

and whose properties are determined by subunit composition

It has been associated with multiple functions| including axon membrane trafficking| axonal homeostasis| mitophagy| adipose differentiation| and hematopoietic stem cell maintenance

It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation

The functioning of this gene is implicated in a wide variety of inflammation-associated disease states

TRADD Polyclonal Antibody, 100ul Hepatocytes consisting of a homodimer ofTumor necrosis factor receptor type 1 associated DEATH domain protein encoded by TRADD is a death domain containing adaptor molecule that interacts with TNFRSF1A TNFR1 and mediates programmed cell death signaling and NF kappaB activation. Tumor necrosis factor receptor type 1 associated DEATH domain protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor of apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated

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