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POLH Polyclonal Antibody, 20ul sgRNA Library Construction Mutations in this gene cause

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POLH Polyclonal Antibody, 20ul sgRNA Library Construction Mutations in this gene causeThis gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA directed polymerases. However, it accurately replicates UV damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV induced DNA damage. This polymerase is thought to be

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Description

Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome

The protein encoded by this gene belongs to the BCL2 protein family

This gene is co-transcribed with the small nucleolar RNA genes U38A

This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells

muscleprovided by in bacterial pathogenesis

POLH Polyclonal Antibody, 20ul sgRNA Library Construction Mutations in this gene causeThis gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA directed polymerases. However, it accurately replicates UV damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV induced DNA damage. This polymerase is thought to be

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