Ret Polyclonal Antibody, 20ul[BT-AP07761] Pathway and Network Analysis ABCC12 is a member of

ABCC12 is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein (ATP binding cassette subfamily C member 12) contains two ATP-binding domains and 12 transmembrane regions

Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activition or by arresting cell growth in G1 phase in a p53-dependent manner

exons 2 and 3 encode the alpha1 and alpha2 domains

9 PCR Tube Adapter

Several different transcript variants encoding different isoforms have been found for APOL1

Ret Polyclonal Antibody, 20ul[BT-AP07761] Pathway and Network Analysis ABCC12 is a member ofRET (ret proto oncogene), a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell surface molecules that transduce signals for cell growth and differentiation. RET plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in RET are associated with the disorders multiple endocrine neoplasia, type IIA, multiple