VCC1 Polyclonal Antibody, 100ul Yeast Expression Atrophin-1 contains a polyglutamine repeat

Atrophin-1 contains a polyglutamine repeat

This protein contains 7 leucine-rich repeats and 12 immunoglobulin-like C2-type domains related to perlecan

which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II

The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors

one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome

VCC1 Polyclonal Antibody, 100ul Yeast Expression Atrophin-1 contains a polyglutamine repeatThe protein encoded by this gene is a mucosal chemokine that attracts immature dendritic cells and blood monocytes to the lungs. The encoded protein also promotes tumorigenesis through an angiogenic activity. Finally, this protein exhibits strong antimicrobial activity against E. coli, S. aureus, Salmonella, P. aeruginosa, and C. albicans. Two transcript variants, one protein coding and the other non protein coding, have been found for this gene.