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SphK2(Phospho Thr614) Polyclonal Antibody, 20ul Sample Library Tubes The protein encoded by this

SKU: 52471844358

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SphK2(Phospho Thr614) Polyclonal Antibody, 20ul Sample Library Tubes The protein encoded by thisThis gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1 phosphate. Sphingosine 1 phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced

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Description

The protein encoded by this gene is predicted to be a five-pass transmembrane protein

Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin but calreticulin is not a Ro/SS-A antigen

CD302 (CD302 molecule) is a C-type lectin receptor involved in cell adhesion and migration

Interacts with the oligomeric lectins MBL2| FCN2 and FCN3

suggesting that it may be involved in extracellular matrix adhesion

SphK2(Phospho Thr614) Polyclonal Antibody, 20ul Sample Library Tubes The protein encoded by thisThis gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1 phosphate. Sphingosine 1 phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced

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