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DOCK 2 Polyclonal Antibody, 20ul Cryogenic Vials The encoded protein may play

SKU: 52526539017

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EUR111.00 EUR155.00

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DOCK 2 Polyclonal Antibody, 20ul Cryogenic Vials The encoded protein may playDedicator of cytokinesis protein 2 encoded by DOCK2 belongs to the CDM protein family. It is specifically expressed in hematopoietic cells, predominantly in the peripheral blood leukocytes, and is involved in remodeling of the actin cytoskeleton required for lymphocyte migration, through the activation of RAC. Mice lacking this gene show a severe impairment in the migration and homing of lymphocytes. These mutant mice also exhibited long term survival

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Description

The encoded protein may play a role in spermatogenesis

specifically designed for use with our MX-M Microplate Mixer

Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes

Earlier papers referred to calreticulin as an Ro/SS-A antigen but this was later disproven

May play a role in hypermutation of immunogobulin genes

DOCK 2 Polyclonal Antibody, 20ul Cryogenic Vials The encoded protein may playDedicator of cytokinesis protein 2 encoded by DOCK2 belongs to the CDM protein family. It is specifically expressed in hematopoietic cells, predominantly in the peripheral blood leukocytes, and is involved in remodeling of the actin cytoskeleton required for lymphocyte migration, through the activation of RAC. Mice lacking this gene show a severe impairment in the migration and homing of lymphocytes. These mutant mice also exhibited long term survival

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