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IGF-IR Polyclonal Antibody, 50ul[BT-AP04397] Cell Separation and Collection Myosin regulatory light chain 12A

SKU: 52536112173

4.5
PLN162.00 PLN187.00

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IGF-IR Polyclonal Antibody, 50ul[BT-AP04397] Cell Separation and Collection Myosin regulatory light chain 12AIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms

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Description

Myosin regulatory light chain 12A is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction

Alternatively spliced transcript variants encoding multiple isoforms have been observed for URI1

which play a role in a wide range of developmental processes

In response to cellular stress and proinflammatory cytokines

induces dimerization and activation of the receptor

IGF-IR Polyclonal Antibody, 50ul[BT-AP04397] Cell Separation and Collection Myosin regulatory light chain 12AIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms

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