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PDS5B Polyclonal Antibody, 100ul Buffers & Solutions This protein contains two conserved

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PDS5B Polyclonal Antibody, 100ul Buffers & Solutions This protein contains two conservedThis gene encodes a protein that interacts with the conserved protein complex termed cohesin. The cohesin complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor suppressor gene.

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Description

This protein contains two conserved domains| an N-terminal RUN domain and a C-terminal DUF4206 domain

Defects in this factor lead to Rosenthal syndrome| a blood coagulation abnormality

Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin

the gene encoding VWA5A maps to human chromosome 11q24

The protein encoded by MATK has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: sRC homology SH2 and SH3 domains

PDS5B Polyclonal Antibody, 100ul Buffers & Solutions This protein contains two conservedThis gene encodes a protein that interacts with the conserved protein complex termed cohesin. The cohesin complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor suppressor gene.

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