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Akt1 Polyclonal Antibody, 50ul[BT-AP00345] General Lab Use Increased expression of this gene

SKU: 52953665398

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PLN162.00 PLN185.00

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Akt1 Polyclonal Antibody, 50ul[BT-AP00345] General Lab Use Increased expression of this geneThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling

This gene encodes a protein containing two conserved tandem RNA recognition motifs

Upon activation of the factor VII

See ZFP93 (MIM 604749) for additional information on zinc finger proteins

Belongs to the peptidase S1 family

Akt1 Polyclonal Antibody, 50ul[BT-AP00345] General Lab Use Increased expression of this geneThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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