Paxillin Polyclonal Antibody, 50ul[BT-AP06957] Serological Pipets The encoded protein lacks detectable

The encoded protein lacks detectable catalytic tyrosine kinase activity

More than 30 loci (SPG1-33) have been implicated in hereditary spastic paraplegia diseases

It is phosphorylated in vivo by Cdk1 during mitosis of the cell cycle

telecanthus and anogenital and renal malformations

and thus plays an important role in lymphocyte differentiation and migration

Paxillin Polyclonal Antibody, 50ul[BT-AP06957] Serological Pipets The encoded protein lacks detectablePXN encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for PXN. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties.