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NPTX2 Polyclonal Antibody, 50ul Lysosome membrane bound isoforms

SKU: 53030844359

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NPTX2 Polyclonal Antibody, 50ul Lysosome membrane bound isoformsThis gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid (AMPA) type glutamate receptors at established synapses, resulting in non apoptotic cell death of dopaminergic nerve cells. Up regulation of this gene in Parkinson disease (PD)

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Description

membrane bound isoforms

subunit:Interacts with FGFR1 and FGFR4

The p53/TP53-cofactor and actin activator activities are regulated via its subcellular location

Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling

It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells

NPTX2 Polyclonal Antibody, 50ul Lysosome membrane bound isoformsThis gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid (AMPA) type glutamate receptors at established synapses, resulting in non apoptotic cell death of dopaminergic nerve cells. Up regulation of this gene in Parkinson disease (PD)

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