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Rictor(Phospho-Thr1135) Rabbit Polyclonal Antibody, 50ul Cryopreservation The mRNA for this gene

SKU: 53081885391

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Rictor(Phospho-Thr1135) Rabbit Polyclonal Antibody, 50ul Cryopreservation The mRNA for this geneRICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient and growth factor derived signals to regulate cell growth (Sarbassov et al. 2004

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Description

The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination

Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics

this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas

Alternative splicing of TAF1 results in multiple transcript variants

One or two of these subunits| together with the well-conserved catalytic subunit| can form the PP1 holoenzyme| where the regulatory subunit functions to regulate substrate specificity and/or targeting to a particular cellular compartment

Rictor(Phospho-Thr1135) Rabbit Polyclonal Antibody, 50ul Cryopreservation The mRNA for this geneRICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient and growth factor derived signals to regulate cell growth (Sarbassov et al. 2004

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