ATF6A Rabbit Polyclonal Antibody, 50ul Bio-Reaction Tube Atrophin-1 contains a polyglutamine repeat

Atrophin-1 contains a polyglutamine repeat

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Diseases associated with OPRD1 include morphine dependence and heroin dependence

transcription regulation

moderate expression is found in amygdala and caudate nucleus

ATF6A Rabbit Polyclonal Antibody, 50ul Bio-Reaction Tube Atrophin-1 contains a polyglutamine repeatThis gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor transducer, and following ER stress induced proteolysis, it functions as a nuclear transcription factor via a cis acting ER