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LSM1 Polyclonal Antibody, 50ul Sampling Tubes Two transcript variants encoding different

SKU: 53148670904

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LSM1 Polyclonal Antibody, 50ul Sampling Tubes Two transcript variants encoding differentThis gene encodes a member of the LSm family of RNA binding proteins. LSm proteins form stable heteromers that bind specifically to the 3' terminal oligo(U) tract of U6 snRNA and may play a role in pre mRNA splicing by mediating U4 U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced

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Description

Two transcript variants encoding different isoforms have been found for CDKL1

Part of the complex F(0) domain

and a key role in cardiovascular homeostasis

Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene

Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF)

LSM1 Polyclonal Antibody, 50ul Sampling Tubes Two transcript variants encoding differentThis gene encodes a member of the LSm family of RNA binding proteins. LSm proteins form stable heteromers that bind specifically to the 3' terminal oligo(U) tract of U6 snRNA and may play a role in pre mRNA splicing by mediating U4 U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced

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