SLP-76(Phospho-Ser376) Rabbit Polyclonal Antibody, 50ul Electronic Pipette Reticulons are necessary for proper

Reticulons are necessary for proper generation of tubular endoplasmic reticulum and likely play a role in intracellular vesicular transport

The protein activates the Beclin1-PI(3)KC3 complex

The encoded protein functions as an adaptor protein that complexes with Cullin 3 and other proteins to form the Cullin 3-based E3 ubiquitin-protein ligase complex

although estimates of its size range from 200 to 2000 kDa with smaller “subunits” being described by some investigators

This enzyme may play a role in bone mineralization

SLP-76(Phospho-Ser376) Rabbit Polyclonal Antibody, 50ul Electronic Pipette Reticulons are necessary for properSLP 76 was originally identified as a substrate of the ZAP 70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP 76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2 terminus contains an acidic