Erbin Rabbit Polyclonal Antibody, 50ul[BT-AP09695] Deep Well Plates The protein encoded by this

The protein encoded by this gene is an activator of MAP3K7/TAK1| which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK

LAMA5 encodes one of the vertebrate laminin alpha chains

Expression of the human protein has been detected in uterus

The different UCPs have tissue-specific expression

Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy| an autosomal recessive disorder of unregulated and high insulin secretion

Erbin Rabbit Polyclonal Antibody, 50ul[BT-AP09695] Deep Well Plates The protein encoded by thisThis gene is a member of the leucine rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.