CCBE1 Polyclonal Antibody, 20ul DNA Fragments 60S ribosomal protein L36 belongs

60S ribosomal protein L36 belongs to the L36E family of ribosomal proteins

the encoded protein effects transcriptional elongation and may help remodel chromatin

However| it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer| stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways| such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase

Also interacts with MAP3K8

Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors

CCBE1 Polyclonal Antibody, 20ul DNA Fragments 60S ribosomal protein L36 belongsThis gene is thought to function in extracellular matrix remodeling and migration. It is predominantly expressed in the ovary, but down regulated in ovarian cancer cell lines and primary carcinomas, suggesting its role as a tumour suppressor. Mutations in this gene have been associated with Hennekam lymphangiectasia lymphedema syndrome, a generalized lymphatic dysplasia in humans.