DNA pol Gamma2 Polyclonal Antibody, 100ul Shakers velocardiofacial syndrome and giant platelet

velocardiofacial syndrome and giant platelet disorder

This member functions as a modulatory subunit

is not routinely typed

an N-terminal DNA-binding domain| a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression

This enzyme acts on histones| and its activity is important for chromatin assembly and chromosome integrity

DNA pol Gamma2 Polyclonal Antibody, 100ul Shakers velocardiofacial syndrome and giant plateletPOLG2 encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The DNA polymerase gamma 2, accessory subunit forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.