MSK1(Phospho Ser212) Polyclonal Antibody, 50ul Endonucleases & Exonucleases the membrane-bound form binds to

the membrane-bound form binds to the endoplasmic reticulum

This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C

are important regulators of vesicular fusion and trafficking

Defects in PAK3 are the cause of non-syndromic mental retardation X-linked type 30 (MRX30)

and may provide a trigger for terminal muscle cell differentiation

MSK1(Phospho Ser212) Polyclonal Antibody, 50ul Endonucleases & Exonucleases the membrane-bound form binds toCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,cofactor: Magnesium.,enzyme regulation: Appears to be activated by multiple phosphorylations on threonine and serine residues. ERK1 2 and MAPK14 p38 alpha may play a role in this process.,Serine threonine kinase required for the mitogen or stress induced phosphorylation of the transcription factors CREB (cAMP response element binding protein) and ATF1 (activating transcription factor 1).