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ANR11 Rabbit Polyclonal Antibody, 50ul Recombinant Protein Expression This gene encodes a classical

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ANR11 Rabbit Polyclonal Antibody, 50ul Recombinant Protein Expression This gene encodes a classicalThis locus encodes an ankryin repeat domain containing protein. The encoded protein inhibits ligand dependent activation of transcription. Mutations in this gene have been associated with KBG syndrome which is characterized by macrodontia distinctive craniofacial features short stature skeletal anomalies global developmental delay seizures and intellectual disability. Alternatively spliced transcript variants have been described. Related pseudogenes

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Description

This gene encodes a classical cadherin and member of the cadherin superfamily

and a single intracytoplasmic catalytic domain

The longest protein isoform encoded by this gene contains an SH3 domain| which is known to be important in intracellular signal transduction

Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C

As compared to cathepsin B| cathepsin L exhibits higher activity toward protein substrates| but has little activity on Z-Arg-Arg-NHMec| and no peptidyl-dipeptidase activity

ANR11 Rabbit Polyclonal Antibody, 50ul Recombinant Protein Expression This gene encodes a classicalThis locus encodes an ankryin repeat domain containing protein. The encoded protein inhibits ligand dependent activation of transcription. Mutations in this gene have been associated with KBG syndrome which is characterized by macrodontia distinctive craniofacial features short stature skeletal anomalies global developmental delay seizures and intellectual disability. Alternatively spliced transcript variants have been described. Related pseudogenes

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