GABAA R beta 1(Phospho Ser434) Polyclonal Antibody, 100ul Immuno Plates Mutations in this gene have

Mutations in this gene have been associated with complex cortical dysplasia with other brain malformations-2

Mutations in this gene are a cause of oblique facial clefting-1

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Catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate

The protein encoded by this gene is a calcium-activated nonselective ion channel that mediates transport of monovalent cations across membranes| thereby depolarizing the membrane

GABAA R beta 1(Phospho Ser434) Polyclonal Antibody, 100ul Immuno Plates Mutations in this gene haveThe gamma aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia.