FEN-1 Polyclonal Antibody, 20ul miRNA / siRNA Synthesis and may participate in the

and may participate in the killing and digestion of engulfed pathogens

uanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP

This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors

Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1)

Transcript variants encoding different isoforms have been noted for CYP11B1

FEN-1 Polyclonal Antibody, 20ul miRNA / siRNA Synthesis and may participate in theFlap endonuclease 1 encoded by FEN1 removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG RAD2 endonuclease family and is