Rb Polyclonal Antibody, 50ul[BT-AP07685] Peptide Library Fully programmable

Fully programmable

Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization| inositol triphosphate production and secretion of IL6 and CSF1

This gene is one of the contiguous genes at 7q11

is a type II membrane glycoprotein that exists as a disulfide-linked homodimer of two identical subunits

SLC1A1 encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes

Rb Polyclonal Antibody, 50ul[BT-AP07685] Peptide Library Fully programmableRB transcriptional corepressor 1 encoded by RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.