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HECW1 Polyclonal Antibody, 20ul Serum subcellular location:In (PubMed:11350957) diffuse granular

SKU: 54323148028

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HECW1 Polyclonal Antibody, 20ul Serum subcellular location:In (PubMed:11350957) diffuse granularE3 ubiquitin protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.,pathway: Protein modification; protein ubiquitination.,Contains 1 C2 domain.,Contains 1 HECT (E6AP type E3 ubiquitin protein ligase) domain.,Contains 2 WW

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Description

subcellular location:In (PubMed:11350957) diffuse granular localization in the cytoplasm surrounding the nucleus

The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver

suggesting that it may play a role in regulating genes in germ cells

LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV)

Studies in both human and mice suggest that PP1 is an important regulator of cardiac function

HECW1 Polyclonal Antibody, 20ul Serum subcellular location:In (PubMed:11350957) diffuse granularE3 ubiquitin protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.,pathway: Protein modification; protein ubiquitination.,Contains 1 C2 domain.,Contains 1 HECT (E6AP type E3 ubiquitin protein ligase) domain.,Contains 2 WW

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