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Ku-70 Polyclonal Antibody, 20ul[BT-AP04896] DNA Synthesis Activity of this protein regulates

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Ku-70 Polyclonal Antibody, 20ul[BT-AP04896] DNA Synthesis Activity of this protein regulatesThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex

It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function

CACNA2D4 encodes a member of the alpha-2/delta subunit family

Alternative splicing results in multiple transcript variants encoding the same isoform

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Ku-70 Polyclonal Antibody, 20ul[BT-AP04896] DNA Synthesis Activity of this protein regulatesThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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