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PI 3-kinase p85 Alpha Polyclonal Antibody, 50ul[BT-AP07144] Bio-Reaction Tube The encoded protein regulates signaling

SKU: 54422701504

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PI 3-kinase p85 Alpha Polyclonal Antibody, 50ul[BT-AP07144] Bio-Reaction Tube The encoded protein regulates signalingPhosphatidylinositol 3 kinase phosphorylates the inositol ring of phosphatidylinositol at the 3 prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. PIK3R1 encodes the 85 kD regulatory subunit. Phosphatidylinositol 3 kinase plays an important role in the metabolic actions of insulin, and a mutation in PIK3R1 has been associated with insulin resistance. Alternative splicing of PIK3R1

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Description

The encoded protein regulates signaling pathways that affect cell proliferation and adhesion

The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems

develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age

Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes

The protein encoded by this gene is specifically expressed in the inner ear| and is located at the interface between the apical surface of the inner ear sensory epithelia and their overlying acellular gels

PI 3-kinase p85 Alpha Polyclonal Antibody, 50ul[BT-AP07144] Bio-Reaction Tube The encoded protein regulates signalingPhosphatidylinositol 3 kinase phosphorylates the inositol ring of phosphatidylinositol at the 3 prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. PIK3R1 encodes the 85 kD regulatory subunit. Phosphatidylinositol 3 kinase plays an important role in the metabolic actions of insulin, and a mutation in PIK3R1 has been associated with insulin resistance. Alternative splicing of PIK3R1

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